Sunday 29 April 2012

Report for the 2012 Diabetes Technology Society Clinical Meeting



This year’s clinical DTS meeting was held at the Omni Hotel in downtown Los Angeles on April 20th-21st. Unlike the large annual meeting of the Society in the Autumn, this one focuses on clinical aspects of the role of technology for diabetes care. As well as the formal meeting, the other benefit of attending is to network with fellow scientist-clinicians, educators and high-level industry attendees. Unsurprisingly, the audience was overwhelmingly US.

As well as discussing the current state of the art in relation to diabetes technologies, there were many glimpses into the future. So what were the take-home messages?

Self-monitoring of blood glucose
The debate about acceptable levels of accuracy for test strips continues but the general impression was that the level of accuracy depends on the patient group – for example better accuracy is needed for those at greatest risk of hypoglycemia.

The hot topic, as far as the audience was concerned related to preventing serious infections in care homes and hospitals (now known as assisted blood glucose monitoring) in relation to the lancets but also the meters per se. The US regulatory authorities are increasingly turning their attention to this topic and industry will have to deal with this.

Fantastic presentation and discussions around structured blood glucose monitoring for people with diabetes not using insulin highlighting the importance of thinking about the timing and frequency of testing and most importantly making sure that clinicians as well as people with diabetes know what to do with the results! This is especially relevant when working out the cost-effectiveness of self-monitoring. 

Continuous Glucose Monitoring
There were detailed descriptions of the role of CGM in certain situations including pregnancy and for children with diabetes and discussion around interpretation of sensor data.  Perhaps there is a need for the creation of a platform for sensor downloads to be more widely available and in a more understandable form for education purposes? The recent findings showing value of CGM in type 2 diabetes were also highlighted.  There was also an update into the potential appearance of implantable glucose sensors. The bottom line – CGM can add value to diabetes care and needs to be more widely available in health-care systems but the costs need to come down! The patient panel eloquently highlighted the good and the not-so-good aspects of sensor technology and their insights would be well worth recording and posting for others to hear.

Insulin Delivery Systems
In a nutshell, everyone is waiting to access smaller patch pumps and the race is on from at least two new companies entering the commercial arena as well as the usual suspects. Key requirements seem to be (a) better connectivity and (b) an absolute requirement for a bolus button on the patch pump. For pens can we have new technologies that date and time stamp the insulin injections and ones that can be downloaded? Experience and data are increasing on the use of CSII in type 2 diabetes – this could have important economic consequences for any healthcare system though! An excellent talk on software guided systems for insulin delivery made the important point that this approach should be more widely sued in Critical Care Units but the real difficult nut to crack remains glucose control elsewhere in the hospital.

Other important take home messages from the meeting were:

1.     Inhaled insulin may still have a future - http://www.mannkindcorp.com/
2.     Telehealth for diabetes care continues to develop and there is increasing interest in using this approach for discrete diabetes monitoring.
3.     Dealing with exercise and insulin remains a difficult challenge but a great deal can be gained by learning from the approach used by elites athletes and their diabetes teams
4.     Work on the artificial pancreas continues to bear fruit – it is likely that a system for overnight closed-loop control will be the first to be widely available although the exact timing is still not clear.

Given that I gave the presentation it is probably no surprise that one take-home message from the Clinical DTS meeting is that social media has the potential to add enormous value to diabetes care although it is still in its infancy. Traditional research funding bodies will need to re-evaluate their approach and methods to allow imaginative trials in this space to happen.

So what next?

From both formal and informal discussions there is a clear need to offer more practical training for whole diabetes teams for common  (and often evidence free) clinical scenarios. With this in mind we are exploring developing this for next year so please keep following developments on http://www.VoyageMD.com

Back to a rain and wind swept UK now!!!